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Memantin HCl

Memantin HCl
Memantin HCl
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Product Code : Memantin HCl
  • Storage
  • Room Temperature
  • Shelf Life
  • 5 years if sealed and store away from direct sun light. Years
  • Molecular Formula
  • C12H21N.HCl
  • Chemical Name
  • Memantin HCl
  • CAS No
  • 41100-52-1
  • Type
  • Other
  • Grade
  • Medicine Grade
  • Usage
  • Memantine is used to treat moderate to severe confusion (dementia) related to Alzheimers disease. It does not cure Alzheimers disease, but it may improve memory, awareness, and the ability to perform daily functions. This medication works by blocking the action of a certain natural substance in the brain (glutamate) that is believed to be linked to symptoms of Alzheimers disease.
  • Appearance
  • White powder
  • Physical Form
  • Powder
  • FOB Port
  • Nhava Sheva / Hazira
  • Payment Terms
  • Telegraphic Transfer (T/T), Letter of Credit at Sight (Sight L/C)
  • Delivery Time
  • 1 Week
  • Sample Available
  • Yes
  • Sample Policy
  • Free samples available with shipping and taxes paid by the buyer
  • Packaging Details
  • 25 kg/drum with double plastic bags inside; packed in a cardboard drum or fiber HDPE drum.
  • Main Export Market(s)
  • Africa, Middle East, Western Europe, Eastern Europe, South America, North America, Central America, Australia, Asia
  • Main Domestic Market
  • All India
  • Certifications
  • WHO, GMP, COA, MSDS, As Per Clients Requirement
Product Description

Product Name : Memantin HCl

Grade : IP / BP / USP

Therapeutic Category : Central Nervous System Agent

CAS No : 41100-52-1

MF: C12H21N.HCl

Use: Alzheimer's disease treatment

Appearance: White powder


A dysfunction of glutamatergic neurotransmission, manifested as neuronal excitotoxicity, is hypothesized to be involved in the etiology of Alzheimer's disease. Targeting the glutamatergic system, specifically NMDA receptors, offers a novel approach to treatment in view of the limited efficacy of existing drugs targeting the cholinergic system.

Memantine is a low-affinity voltage-dependent uncompetitive antagonist at glutamatergic NMDA receptors. By binding to the NMDA receptor with a higher affinity than Mg2+ ions, memantine is able to inhibit the prolonged influx of Ca2+ ions which forms the basis of neuronal excitotoxicity. The low affinity and rapid off-rate kinetics of memantine at the level of the NMDA receptor-channel, however, preserves the physiological function of the receptor as it can still be activated by the relatively high concentrations of glutamate released following depolarization of the presynaptic neuron.


Additional Information

The most common markets for this product include the following countries. Please inquire with us if your country or region is not listed:


Asia: Afghanistan, Israel, Jordan, Pakistan, Russia, Saudi Arabia, Singapore, Syria, Philippines, Turkey, Turkmenistan, Uzbekistan, Yemen, Vietnam, Indonesia, Malaysia, Iran, Tajikistan, etc.

Africa: South Africa, Uganda, Nigeria, Ghana, Kenya, Mauritius, Botswana, Egypt, Ethiopia, Libya, Sudan, Congo, Gambia, Ivory Coast , etc.

North & South America: USA, Canada, Panama, Trinidad and Tobago, Costa Rica, Puerto Rico, Dominican Republic, Argentina, Guatemala, Guyana, Peru, Bolivia, Venezuela , Brazil, Bahamas, Ecuador, etc .

Europe: Austria , Azerbaijan, Belarus, Belgium, Cyprus, Czech Republic, Denmark, France, Georgia, Germany, Hungary, Ireland, Iceland, Netherlands, Norway, Poland, Spain, Sweden, Switzerland, Ukraine, United Kingdom (UK) , Latvia, etc.

OCEANIA: Australia, New Zealand, Fiji, etc.


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