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Rabeprazole 20 Mg vial
We Salvavidas Pharmaceutical Pvt Ltd are a leading Manufacturer and Exporter of Rabeprazole vial in different strength and packing. Our manufacturing facility is certified with WHO-GMP.
Rabeprazole sodium belongs to a class of antisecretory compounds (substituted benzimidazole proton-pump inhibitors ) that do not exhibit anticholinergic or histamine H2-receptor antagonist properties, but suppress gastric acid secretion by inhibiting the gastric H+, K+ATPase at the secretory surface of the gastric parietal cell. Because this enzyme is regarded as the acid (proton) pump within the parietal cell, rabeprazole has been characterized as a gastric PPI. Rabeprazole blocks the final step of gastric acid secretion.
In gastric parietal cells, rabeprazole is protonated, accumulates, and is transformed to an active sulphenamide. When studied in vitro, rabeprazole is chemically activated at pH 1.2, with a half-life of 78 seconds. It inhibits acid transport in porcine gastric vesicles, with a half-life of 90 seconds.
Used for duodenal ulcer, gastro esophageal reflux disease (GERD), and Zollinger-Ellison (gastric acid hyper secretion) syndrome.